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Semaglutide provides a stabilized synthetic 31-amino acid GLP-1 analogue engineered with an Aib substitution at position 8 and a C18 fatty acid side chain at lysine-26. Extensively utilized in analytical laboratories as a standard benchmark control for evaluating competitive receptor binding kinetics, DPP-4 enzymatic degradation resistance, and downstream insulinotropic pathways. Purity ≥99% validated by RP-HPLC and mass spectrometry. Strictly for research use only.

Chemical & Analytical Specifications

Compound Identifier Semaglutide (Selective GLP-1 Agonist)
Sequence / Structure His-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-{gamma-Glu-C18-diacid}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly
Molecular Formula C187H291N45O59
Molecular Weight 4113.58 g/mol
CAS Number 910463-68-2
Purity Specification ≥99.0% (HPLC & Mass Spectrometry)
Supplied Format Lyophilized powder in borosilicate glass vial
Research Classification Incretin receptor benchmark standard

Laboratory Handling & Solvent Protocols

To preserve structural integrity and peptide purity, lyophilized materials should be maintained at -20°C in an airtight container protected from ambient moisture and light. Reconstitution should be conducted under sterile conditions using bacteriostatic water (0.9% benzyl alcohol) or sterile laboratory saline. Allow the diluent to run gently down the interior vial wall; avoid vigorous shaking or vortexing to prevent shear-induced degradation. Reconstituted aliquots must be stored at 2°C to 8°C and evaluated within 28 to 30 days.

REGULATORY COMPLIANCE NOTICE All èvelan research products are strictly synthesized and supplied for laboratory research, analytical characterization, and scientific assay evaluation only. These materials are not intended, formulated, or approved for human, clinical, veterinary, or diagnostic application. Distribution is restricted to authorized personnel who affirm adherence to relevant institutional and laboratory safety protocols.

Semaglutide (Selective GLP-1 Agonist)

$256.00

Research Pathways & Profile

Semaglutide provides a stabilized synthetic 31-amino acid GLP-1 analogue engineered with an Aib substitution at position 8 and a C18 fatty acid side chain at lysine-26. Extensively utilized in analytical laboratories as a standard benchmark control for evaluating competitive receptor binding kinetics, DPP-4 enzymatic degradation resistance, and downstream insulinotropic pathways. Purity ≥99% validated by RP-HPLC and mass spectrometry. Strictly for research use only.

Format & Concentration: 5mg Lyophilized Vial
≥99% HPLC Analytical Standard
Synthesized in Certified Facility
Direct Express Lab Fulfillment
Analytical Specifications & Sequence

Sequence: His-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-{gamma-Glu-C18-diacid}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly | Formula: C187H291N45O59 | Molecular Weight: 4113.58 g/mol | CAS Number: 910463-68-2 | Purity: ≥99.0% (RP-HPLC, ESI-MS) | Sterile Lyophilized Formulation.

Handling, Solvent & Storage Guidelines

Laboratory Assay Standard. Storage: -20°C (lyophilized powder, protected from light) or 2°C to 8°C (short-term reconstituted solution). Reconstitution: Bacteriostatic water (0.9% benzyl alcohol) via sterile interior wall flow without vortexing. Strictly prohibited for human, veterinary, or clinical use.

1All peptide compounds cataloged are intended exclusively for laboratory research, biochemical assays, and analytical characterization. Strictly not for human, veterinary, diagnostic, or therapeutic administration.
2Analytical purity (≥99%) is validated via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). Compound integrity is dependent on adherence to cold-chain storage and inert handling protocols.
3The acquiring entity assumes sole responsibility for regulatory compliance, laboratory safety protocols, and safe handling in accordance with federal, state, and local standards. èvelan expressly disclaims liability for off-label or unapproved application.
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